Plasmapheresis
An Essential Therapeutic Tool
Exploring the potential of plasmapheresis in the treatment of autoimmune diseases and other complex conditions.
Pathologies with First-Line Indication (Category I)
Guillain-Barré Syndrome
It helps eliminate antibodies that attack the peripheral nervous system, improving neurological recovery.
Polineuropatía Desmielinizante Inflamatoria Crónica (CIDP)
Opción de tratamiento clave para eliminar anticuerpos que dañan la mielina, mejorando la función nerviosa.
Goodpasture Syndrome
Vital para eliminar anticuerpos anti-membrana basal glomerular, preservando la función renal y pulmonar.
Other Pathologies with Proven Benefits
- Essential Mixed Cryoglobulinemia: Eliminates cryoglobulins that can cause vasculitis and organ damage, relieving symptoms and preventing complications.
- Hyperviscosity in Monoclonal Gammopathies: Rapidly reduces blood viscosity in conditions such as Waldenström’s Macroglobulinemia or Multiple Myeloma.
- Systemic Lupus Erythematosus (in severe cases with vital organ involvement or refractory to other treatments).
- Rheumatoid Arthritis (in specific and refractory cases).
- Dermatomyositis and Polymyositis (especially in macrophage activation syndrome).
- Catastrophic Antiphospholipid Syndrome.
- Granulomatosis with Polyangiitis (in severe cases with alveolar hemorrhage or acute renal failure).
Plasmapheresis and Rheumatoid Factor
In rheumatoid arthritis and other autoimmune diseases, the immune system mistakenly attacks healthy tissues, especially the joints.
Rheumatoid factor, along with other autoantibodies and immune complexes, contributes to inflammation and joint damage. Plasmapheresis removes these substances from plasma, reducing the circulating load of autoantibodies and immune complexes. This decreases inflammatory activity and associated tissue damage, improving the clinical symptoms of the disease.